a model of colonic crypts using sbml spatial

a model of colonic crypts using sbml spatial

;Carlo Maj;Marco Antoniotti;Daniele Ramazzotti
ama journal of ethics 2013 Vol. 130 pp. 74-78
52
maj2013electronica

Abstract

The Spatial Processes package enables an explicit definition of a spatial environment on top of the normal dynamic modeling SBML capabilities. The possibility of an explicit representation of spatial dynamics increases the representation power of SBML. In this work we used those new SBML features to define an extensive model of colonic crypts composed of the main cellular types (from stem cells to fully differentiated cells), alongside their spatial dynamics.

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