increased trypanosoma brucei cathepsin-l activity inhibits human serum-mediated trypanolysis

increased trypanosoma brucei cathepsin-l activity inhibits human serum-mediated trypanolysis

;Sam Alsford
povolžskaâ arheologiâ 2014 Vol. 1 pp. 270-272
142
alsford2014microbialincreased

Abstract

Most African trypanosomes, including the veterinary species Trypanosoma brucei brucei and T. congolense are susceptible to lysis by human serum. A recent study by Alsford et al. [PLoS Pathogens (2014) 10, e1004130] has identified a T. b. brucei lysosomal cathepsin with an inhibitory effect on human serum’s trypanolytic action.

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