This paper aims to validate the capability of renewable generation (ReGen) plants to provide online voltage control coordination ancillary service to the system operators in smart grids. Simulation studies about online coordination concepts from ReGen plants have already been identified in previous publications. However, here, the results are validated through a real-time Hardware-In-the-Loop framework using an exemplary benchmark grid area in Denmark as a base case that includes flexible renewable power plants providing voltage control functionality. The provision of voltage control support from ReGen plants is verified on a large-scale power system against the baseline scenario, considering the hierarchical industrial controller platforms used nowadays in power plants. Moreover, the verification of online voltage control support is carried out by taking into account a communication network as well as the associated data traffic patterns obtained from a real network. Based on the sets of recordings, guidelines and recommendations for practical implementation of the developed control algorithms for targeted ancillary service are made. This provides a deep insight for stakeholders, i.e., wind turbine and photo-voltaic system manufacturers and system operators, regarding the existing boundaries for current technologies and requirements for accommodating the new ancillary services in industrial application.