This paper examined family relationship and bullying behaviour among secondary school students with disabilities in Ogbomoso South, Oyo State, Nigeria. The research design employed for this study was descriptive method of the correlational survey type. The population for this study comprises all secondary school students with disabilities in Ogbomoso South, Oyo State. Two questionnaires were used to collect the necessary data. Bullying Prevalence Questionnaire (BPQ) was adopted from Rigby and Slee (1994). To measure family relationship, the instrument in this section was adopted from Nuhu (2013). Percentage was used to answer the research questions, while Pearson Product Moment Correlation (PPMC) statistical technique was used to test the generated hypothesis. The finding of this study revealed that majority of the respondents’ family relationship was negative. The finding also revealed that majority of the respondents bullying behaviour was low. Also, the finding of this study revealed that there is a significant relationship between family relationship and bullying behaviour among secondary school students with disabilities in Ogbomoso South, Oyo State, Nigeria. It was recommended that for bullying to be reduced, the Ministry of Education is responsible for the welfare of people and their development