Besides the traditional strong and electromagnetic decay modes, Υ(nS) meson can also decay through the weak interactions within the standard model of elementary particle. With anticipation of copious Υ(nS) data samples at the running LHC and coming SuperKEKB experiments, the two-body nonleptonic bottom-changing Υ(nS)→Bc⁎π,Bc⁎K decays (n=1,2,3) are investigated with perturbative QCD approach firstly. The absolute branching ratios for Υ(nS)→Bc⁎π and Bc⁎K decays are estimated to reach up to about 10-10 and 10-11, respectively, which might possibly be measured by the future experiments.