This article focuses on the efficiency of scientific knowledge involved in the context of managing a particular socio-environmental as that composed by Amazon. In a first part, we introduce the actual tools used to create and disseminate knowledge among scientists and to stakeholders. In the second part, we give a structural framework, concerning the co-construction of an interdisciplinary scientific knowledge on a specific geographical region. This structural framework, which is as mathematical object "free of context", provides a contextual efficiency of scientific work when it combines multi-disciplinarity, interdisciplinarity and transdisciplinarity.