Structural analysis of the formation and evolution processes of structural microdestruction with the tran-sition to macrorestriction occurring during plastic deformation of masonry under biaxial stresses. The dependencies that determine the amount of the plastic phase of the deformation of masonry. Identified processes and their corre-sponding strength criteria, which play a key role in the implementation phase of plastic deformation. It is shown that plastic deformation of masonry under biaxial stresses occurs when the physical line operation of the basic ma-terials of masonry (brick and mortar). Found that the plastic properties of masonry under biaxial stresses are deter-mined by the processes occurring at the nodes of contact interaction of brick and mortar in horizontal and vertical joints. According to the results of numerical studies the values of the coefficients of ductility of masonry at different variants of mechanical characteristics of brick, mortar and adhesive strength of their interaction.