biomimetic strategies for bone repair and regeneration

biomimetic strategies for bone repair and regeneration

;Maria G. Raucci;Luigi Ambrosio;Vincenzo Guarino
carbon 2012 Vol. 3 pp. 688-705
178
raucci2012journalbiomimetic

Abstract

The osseointegration rate of implants is related to their composition and surface roughness. Implant roughness favors both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate (Ca-P) coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. It has been clearly shown in many publications that Ca-P coating accelerates bone formation around the implant. This review discusses two main routes for the manufacturing of polymer-based osteoconductive scaffolds for tissue engineering, namely the incorporation of bioceramic particles in the scaffold and the coating of a scaffold with a thin layer of apatite through a biomimetic process.

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207721
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10.3390/jfb3030688
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