This report describes the ultrasonographic differential diagnosis of different types of swellings affecting (28) farm animals. The swellings were, abscess (11), cyst (2), hematoma (2), hernia (9) and urethral diverticulum (4). The swellings varied sonographically according to the type, duration, content and location. Cases suffering the same type of swellings may have some degree of difference in echogenicity according to the period of the swelling. Abscesses appeared as hypo/hyperechoic structures with distinct hyperechoic well-developed capsule. Recent hematomas were anechoic with a well demarcated wall, with increased duration, the hematoma gradually became more echoic and textured. The hernial ring was determined as a discontinuation of the abdominal wall echogenicity and the hernial contents were clearly evaluated via ultrasonography. Recent cysts resembled hematoma in compartmentalization but the location and case history helped the differential diagnosis. Urethral dilatation appeared sonographically as an anechoic to hypoechoic homogenous structure with well demarcated wall and acoustic enhancement. Ultrasonography could be considered a successful, noninvasive, rapid technique for differential diagnosis of different types of swellings in farm animals. It could be easily used under field conditions to screen the lesions before the surgical operations and to fellow up the cases after surgery.