AIM: To develop intersectoral interventions fot overcoming stigmatizing conceptions of mental health-disease process, experiencing the role of the nurse in the context of psychosocial care. METHODOLOGY: This is a descriptive experience report of qualitative approach, implemented in the city of Pesqueira, PE, Brazil, from February to December 2015. RESULTS: We developed psychosocial interventions contributing to discussions on stigma with health professionals and users of a basic health unit. We promoted awareness of the indiscriminate use of psychotropic drugs and openness to new health care models, such as complementary and integrative practices. CONCLUSIONS: The stigma of madness makes it denied to the person in mental suffering their citizenship. The rehabilitation is still difficult because mental illness is interpreted as transgressing social norms, which demand of multidisciplinary health team’s interventions in the territory and with the community.