Diabetic retinopathy is a complication caused by diabetes mellitus. Diabetic retinopathy, if not handled properly can lead to blindness. A necessary step to prevent blindness is early detection. Early detection can be done by finding the initial symptoms that microaneurysm. In this research, a system made to detect diabetic retinopathy using algorithms detection microaneurysm with mathematical morphology. The algorithm is divided into three stages of preprocessing, detecting candidate microaneurysm and postprocessing.  In this research, the system will be made by using a raspberry pi as the media. To see how well the system detects diabetic retinopathy, the test will be done. in the tests performed, system obtained an accuracy of 90%, sensitivity 90, and specificity of 55% using data diaretdb1. While testing using data from e-ophtha obtained results with an accuracy of 70.5%, a sensitivity of 80% and a specificity of 60%.