synthesis of conformationally constrained aryl- or heteroarylpiperazinyl derivatives of selected imides as 5-ht1a receptor ligands
Abstract
The preparation of a number of cyclic imide 5-HT1A receptor ligandderivatives has been described. Their structures were conformationally constrained byintroducing rigid linkers containing unsaturated bonds or aromatic benzene rings. Thesecompounds are expected to possess anxiolytic and antidepressant activity.
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193167
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193167
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10.3390/11080615
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