mind the gap: how some viruses infect their hosts

mind the gap: how some viruses infect their hosts

;Peter E. Prevelige
International journal of pharmaceutics 2010 Vol. 2 pp. 2536-2540
129
prevelige2010virusesmind

Abstract

Cryo-electron microscopy (Cryo-EM) and cryo-electron tomography (Cryo-ET) provide structural insights into complex biological processes. The podoviridae are dsDNA containing phage with short, non-contractile tails which nevertheless translocate their DNA into the cytoplasm of their host cells. Liu et al. [1] used a combination of cryo-EM and cryo-ET to study the structural changes accompanying infection of P. marinus by the phage P-SSP7 and thereby provide unique molecular insight into the process by which the DNA transits from phage to host during infection.

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192157
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