rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy

rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy

;Kelly W Burak;Mark G Swain;Tania Santodomino-Garzon;Samuel S Lee;Stefan J Urbanski;Alexander I Aspinall;Carla S Coffin;Robert P Myers
indian journal of pharmacology 2013 Vol. 27 pp. 273-280
139
burak2013canadianrituximab

Abstract

BACKGROUND: Although most patients with autoimmune hepatitis (AIH) respond to treatment with prednisone and/or azathioprine, some patients are intolerant or refractory to standard therapy. Rituximab is an anti-CD20 monoclonal antibody that depletes B cells and has demonstrated efficacy in other autoimmune conditions.

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186109
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