Magnetohydrodynamic (MHD) boundary layer flow of a nanofluid over an exponentially stretching sheet was studied. The governing boundary layer equations are reduced into ordinary differential equations by a similarity transformation. The transformed equations are solved numerically using the Nactsheim-Swigert shooting technique together with Runge-Kutta six-order iteration schemes. The effects of the governing parameters on the flow field and heat transfer characteristics were obtained and discussed. The numerical solutions for the wall skin friction coefficient, the heat and mass transfer coefficient, and the velocity, temperature, and concentration profiles are computed, analyzed, and discussed graphically. Comparison with previously published work is performed and excellent agreement is observed.