il-1β in irrigation fluid and mrna expression in synovial tissue of the knee joint as therapeutic markers of inflammation in collagen antibody-induced arthritis
international journal of psychology : journal international de psychologie2009Vol. 26pp. 1-7
235
chia2009diseaseil-1
Abstract
Objective: We studied the relationship between the severity of inflammation and IL-1β production and relative expression level of IL-1β mRNA in irrigation fluid and synovial tissue obtained from the knee joint during the acute stage of a murine model of type II collagen antibody-induced arthritis (CAIA). This model is used to identify potential therapeutic markers for treating rheumatoid arthritis.