asymmetric synthesis of 1,3-oxazolidine derivatives with multi-component reaction and research of kinetic resolution

asymmetric synthesis of 1,3-oxazolidine derivatives with multi-component reaction and research of kinetic resolution

;Xiao-Wei Hong;Yu-Qiang Zhou;Cui-Bing Bai;Nai-Xing Wang;Yalan Xing;Wei Zhang;Yan-Jing Wang;Xing-Wang Lan;Yu Xie;Yi-He Li
Journal of ethnopharmacology 2015 Vol. 20 pp. 17208-17220
170
hong2015moleculesasymmetric

Abstract

An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed.

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179670
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10.3390/molecules200917208
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