isolation, characterization and antibacterial activity screening of anthocyanidine glycosides from alchornea cordifolia (schumach. and thonn.) mull. arg. leaves

isolation, characterization and antibacterial activity screening of anthocyanidine glycosides from alchornea cordifolia (schumach. and thonn.) mull. arg. leaves

;Donatus Ebere Okwu;Nneka Ukanwa
Journal of pharmaceutical and biomedical analysis 2010 Vol. 7 pp. 41-48
124
okwu2010e-journalisolation,

Abstract

From the ethanolic extract of the leaves of Alchornea cordifolia (Schumach. and Thonn.) Mull. Arg,, 5–methyl 4’ -propenoxy anthocyanidines 7-O-β-D – diglucopyranoside was isolated. The structure was elucidated using NMR spectroscopy in combination with IR and MS spectral data. Antibacterial studies showed that the isolated compound successfully inhibited Pseudomonas aerguinosa, Escherichia coli, Proteus mirabilis, Klebsiella pueumonia and Staphylococcus aureus. This result authenticates the use of the plant in phytomedicine for disease prevention and treatment of infections.

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173625
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10.1155/2010/586179
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