The role of knowledge of God in the encounter with God in preaching In an era of modernism and postmodernism homiletics is confronted with the problem of reference to God in preaching. According to current epistemologies we cannot have any knowledge of God that can be defended as true knowledge in the forum of academic discourse. In reformed theological theory, according to Calvin, knowledge of God, knowledge of ourselves in the eyes of God, as well as of salvation in Christ is a sine qua non for an encounter with God in preaching in the context of the worship service. This article proceeds from the theological stance that we can find this knowledge only in Scripture through the work of the Spirit. Recent empirical research in Reformed Churches in the Netherlands has shown that church members attend the services expecting to have an encounter with God. The sermon in this expected encounter is still very important for them. A homiletical theory that works with these presuppositions (knowledge of God) has a further problem. There is a growing Biblical illiteracy in Western societies – also in South Africa. As an answer to this problem the author proposes that the teaching sermon along the lines of Calvin’s position on preaching should get more attention in our day.