The use of graphene oxide-based coatings on optical fibers are investigated, aiming to tune the reflectivity of optical fiber surfaces for use in precision sensing devices. Graphene oxide (GO) layers are successfully deposited onto optical fiber ends, either in cleaved or hollow microspheres, by mounting combined bilayers of polyethylenimine (PEI) and GO layers using the Layer-by-Layer (LbL) technique. The reflectivity of optical fibers coated with graphene oxide layers is investigated for the telecom region allowing to both monitor layer growth kinetics and cavity characterization. Tunable reflective surfaces are successfully attained in both cleaved optical fibers and hollow microsphere fiber-based sensors by simply coating them with PEI/GO layers through the LbL film technique.