translocation of clostridium difficile toxin b across polarized caco-2 cell monolayers is enhanced by toxin a

translocation of clostridium difficile toxin b across polarized caco-2 cell monolayers is enhanced by toxin a

;Tim Du;Michelle J Alfa
computer science 2004 Vol. 15 pp. 83-88
228
du2004canadiantranslocation

Abstract

Clostridium difficile is the etiological agent of antibiotic-associated diarrhea; the most common form of nosocomial infectious diarrhea. The basis for the shock-like systemic symptoms observed in severe cases of this infection are not known. It is hypothesized that the invasion of C difficile toxins A and/or B from the gut mucosa may contribute to these symptoms.

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167342
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10.1155/2004/292580
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