translocation of clostridium difficile toxin b across polarized caco-2 cell monolayers is enhanced by toxin a
;Tim Du;Michelle J Alfa
computer science2004Vol. 15pp. 83-88
228
du2004canadiantranslocation
Abstract
Clostridium difficile is the etiological agent of antibiotic-associated diarrhea; the most common form of nosocomial infectious diarrhea. The basis for the shock-like systemic symptoms observed in severe cases of this infection are not known. It is hypothesized that the invasion of C difficile toxins A and/or B from the gut mucosa may contribute to these symptoms.