Selected appropriate cropping patterns, especially high-value crops such as saffron, shows that the pattern of cultivation of these crops can facilitate the achievement of the objectives of rural development programs. In recent years, saffron cultivation considerably has been increased in parts of the city of Nishapur like Isaac Abad district which altered the pattern of crop cultivation from onion to saffron cultivation. The purpose of this study was to identify factors that influence the development pattern of saffron, and the economic and social consequences of the mentioned districts. This study was conducted based on library information and field collected data. A random sampling method was used. The sample size was calculated using Cochran equation, the number of calculated samples were 220 Isaac Abad district saffron grower. Data was analyzed by Pierson Correlation methods. The results showed that geographical factor and attractions in the consumer market were the most important factors in the spread pattern of saffron cultivation in the region. In order to maintain the local potential is also planning to expand the crop pattern deserves more attention to geographical factors.