The commentary to the Hippocratic treatise De humoribus, which was accepted as an authentic Galenic work till recent times, uses to be nowadays assigned to a mid-XVIth. century author of false ancient manuscripts, the Greek Andreas Darmarios. In spite of this, the text presents several kinds of problems that suggest a careful revisiting of the question. This article presents some of such problems and looks for a different explanation by means of the interaction of the languages involved in the transmission of the text.