The new energy and regulatory scenarios on European and Italian level require a review of the regional energy strategies. Transitioning the global economy from fossil fuels to renewable energy sources has been identified as a key strategy for mitigating climate change. Energy sector transformation needs smart policies. The Lazio region is drawing up a new strategy for sustainable energy that aims to define the necessary conditions for development of a regional energy system increasingly turned to the use of renewable sources and efficient energy use as a means for greater environmental protection, in particular for the purpose of reduction of greenhouse gases (GHG). The strategy aims to facilitate the transition to a low carbon economy by increasing energy production from renewable sources, fostering a green economic recovery and the creation of green jobs in Lazio Region.