Abstract The way of life of Lampung people, Piil Pesenggiri, essentially is related to existence of human being correlating to God, other human, and nature. From the axiological dimension, Piil Pesengiri contains some values, such as divinity, religiousity, spirituality, morality, intellectuality, individuality, sociality, and material. Those values can be pressed into three values: divinity, humanity, and vitality. Strategy of cultural development in Lampung must refer to the values of Piil Pesenggiri. It focus on political system of leadership/ power, economy, environment and education. The reason is governmental, economical, and environmental policy philosophically can impact and form mindset and lifestyle of Lampung people. Keywords: Piil Pesenggiri, value of divinity, value of humanity, value of vitality.