This paper investigates the integral characteristics of the evaporation of water droplets (the initial diameter 4–6 mm) during their motion in flames obtained through the combustion of typical flammable liquids for various purposes, such as kerosene and denatured alcohol. We performed the experiments using high-speed video cameras and panoramic cross-correlation techniques PTV and SP. The difference between evaporation rates under appropriate conditions has been defined. The influence of a droplet initial size on evaporation rate has been demonstrated.