Through the study on high temperature creep data of HP heat resistant alloy, a prediction method of high temperature creep deformation based on Zc parameter was proposed. The creep resistance of HP heat resistant alloy was predicted by this method. The results indicate that the predicted data are in good agreement with the HP heat resistant alloy creep experimental data at 1000,980℃ and 930℃. At the same time, the creep rupture life of heat resistant alloy was evaluated by this method, the results show that the predicted principal curves agree well with the experimental data.