This paper presents the investigation on surface integrity, material removal rate and wire wear ratio of Nimonic 80A using WEDM process. Taguchi's design of experiments methodology has been used for planning and designing the experiments. All of the input parameters and two factors interactions have been found to be statically significant for their effects on the response of interest. SEM was performed on the machined samples to investigate the effect and microstructure of the samples after machining. A higher pulse-on time setting leads to thicker recast layer. At lower value of pulse-on time and higher value of pulse-off time, the wire deposition on the machined surface is low.