in vitro assessment of optical properties of blood by applying the extended huygens-fresnel principle to time-domain optical coherence tomography signal at 1300 nm

in vitro assessment of optical properties of blood by applying the extended huygens-fresnel principle to time-domain optical coherence tomography signal at 1300 nm

;Dan P. Popescu;Michael G. Sowa
Chemistry, an Asian journal 2008 Vol. 2008 pp. -
270
popescu2008internationalin

Abstract

A direct method for the measurement of the optical attenuation coefficient and the scattering anisotropy parameter based on applying the extended Huygens-Fresnel principle to optical coherence tomography images of blood is demonstrated. The images are acquired with a low-power probing beam at the wavelength of 1300 nm. Values of 12.15 mm−1 and 0.95 are found for the total attenuation coefficient and the scattering anisotropy factor, respectively. Also, as a preliminary step, the optical refraction index is determined with a precision of two decimal numbers directly from optical coherence images. The total attenuation coefficient and the scattering anisotropy factor are determined with precisions within experimental error margins of 5% and 2%, respectively. Readable OCT signal is obtained for a maximum propagation of light into blood of 0.25 mm. At the maximum probed depth, the measured signal is almost 103 smaller than its initial intensity when entering the sample.

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ID: 140041
Ref Key: popescu2008internationalin
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140041
Unique Identifier:
10.1155/2008/591618
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