attenuation of nad[p]h:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced tgfβ signaling
Current Language EN
English English Türkçe Türkçe Español Español Português Português Pусский Pусский Filipino Filipino Tiếng Việt Tiếng Việt हिन्दी हिन्दी العربية العربية বাংলা বাংলা Deutsch Deutsch 中文 中文

attenuation of nad[p]h:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced tgfβ signaling

;Dinesh Thapa;Shih-Bo Huang;Amanda R. Muñoz;Xiaoyu Yang;Roble G. Bedolla;Chia-Nung Hung;Chun-Liang Chen;Tim H.-M. Huang;Michael A. Liss;Robert L. Reddick;Hiroshi Miyamoto;Addanki P. Kumar;Rita Ghosh
biotechnology & biotechnological equipment 2020 Vol. 3 pp. 1-12
169
thapa2020communicationsattenuation

Abstract

Thapa et al find that depletion of the antioxidant enzyme NAD[P]H:Quinone Oxidoreductase 1 (NQO1) accelerates prostate tumorigenesis and induces the epithelial-to-mesenchymal transition by activating TGFβ signaling. They also find that low NQO1 is associated with mesenchymal signature and biochemical recurrence in clinical samples.

Keywords

Biology (General)

Access

DOI:
10.1038/s42003-019-0720-z
URL:
http://link.springer.com/article/10.1038/s42003-01...

Citation

ID: 139259
Ref Key: thapa2020communicationsattenuation
Use this key to autocite in SciMatic or Thesis Manager

References

References

No Bibliography

Blockchain Verification

Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
139259
Unique Identifier:
10.1038/s42003-019-0720-z
Network:
Scimatic Chain (ID: 481)
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
5/5
Creates 1,000,000 NFT tokens for this article
Token Features:
  • ERC-1155 Standard NFT
  • 1 Million Supply per Article
  • Transferable via MetaMask
  • Permanent Blockchain Record
Blockchain QR Code
Scan with Saymatik Web3.0 Wallet
Gas fees required in SCI Coins
Buy SCI

Saymatik Web3.0 Wallet

Google Play
App Store