Cloud fraction (CF) is known as the dominant modulator of Earth’s radiative fluxes. Ground-based CF observations are useful to characterize the cloudiness of a specific site and are valuable for comparison with satellite observations and numerical models. We present for the first time CF statistics (relative to liquid clouds only) for Bern, Switzerland, derived from the observations of a ground-based microwave radiometer. CF is derived with a new method involving the analysis of the integrated liquid water distribution measured by the radiometer. The 10-year analyzed period (2004–2013) allowed us to compute a CF climatology for Bern, showing a maximum CF of 60.9% in winter and a minimum CF of 42.0% in summer. The CF monthly anomalies are identified with respect to the climatological mean values, and they are confirmed through MeteoSwiss yearly climatological bulletins. The CF monthly mean variations are similar to the observations taken at another Swiss location, Payerne, suggesting a large-scale correlation between different sites on the Swiss Plateau. A CF diurnal cycle is also computed, and large intraseasonal variations are found. The overall mean CF diurnal cycle, however, shows a typical sinusoidal cycle, with higher values in the morning and lower values in the afternoon.