efficient microwave-assisted synthesis of 5-deazaflavine derivatives
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efficient microwave-assisted synthesis of 5-deazaflavine derivatives

;Justo Cobo;José M. de la Torre;Manuel Nogueras;Jairo Quiroga;Luis Gabriel López;Dency José Pacheco;Jorge Trilleras
Journal of ethnopharmacology 2010 Vol. 15 pp. 7227-7234
161
cobo2010moleculesefficient

Abstract

A series of pyrimido[4,5-b]quinolines  (5-deazaflavines), were synthesized by microwave assisted intramolecular cyclization. The N4-substituted-2,4-diamino-6-chloro-pyrimidine-5-carbaldehydes, were prepared by selective monoamination of 2-amino-4,6-dichloropyrimidine-5-carbaldehyde with aliphatic and aromatic amines.

Keywords

Microwave cyclocondensation

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DOI:
10.3390/molecules15107227
URL:
http://www.mdpi.com/1420-3049/15/10/7227/

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ID: 131558
Ref Key: cobo2010moleculesefficient
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