Impact of Different Serum Potassium Levels on Postresuscitation Heart Function and Hemodynamics in Patients with Nontraumatic Out-of-Hospital Cardiac Arrest

Impact of Different Serum Potassium Levels on Postresuscitation Heart Function and Hemodynamics in Patients with Nontraumatic Out-of-Hospital Cardiac Arrest

Lin, Yan-Ren;Syue, Yuan-Jhen;Lee, Tsung-Han;Chou, Chu-Chung;Chang, Chin-Fu;Li, Chao-Jui;Lin, Yan-Ren;Syue, Yuan-Jhen;Lee, Tsung-Han;Chou, Chu-Chung;Chang, Chin-Fu;Li, Chao-Jui;
bioinorganic chemistry and applications 2018 Vol. 2018
455
yanren2018impactbioinorganic

Abstract

Background. Sustained return of spontaneous circulation (ROSC) can be initially established in patients with out-of-hospital cardiac arrest (OHCA); however, the early postresuscitation hemodynamics can still be impaired by high levels of serum potassium (hyperkalemia). The impact of different potassium levels on early postresuscitation heart function has remained unclear. We aim to analyze the relationship between different levels of serum potassium and postresuscitation heart function during the early postresuscitation period (the first hour after achieving sustained ROSC). Methods. Information on 479 nontraumatic OHCA patients with sustained ROSC was retrospectively obtained. Measures of early postresuscitation heart function (rate, blood pressure, and rhythm), hemodynamics (urine output and blood pH), and the duration of survival were analyzed in the case of different serum potassium levels (low: 5 mmol/L). Results. Most patients (59.9%,

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