Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

Saltz J;Gupta R;Hou L;Kurc T;Singh P;Nguyen V;Samaras D;Shroyer KR;Zhao T;Batiste R;Van Arnam J; ;Shmulevich I;Rao AUK;Lazar AJ;Sharma A;Thorsson V;;
Cell reports 2018 Vol. 23 pp. -
272
j2018cellspatial

Abstract

Beyond sample curation and basic pathologic characterization, the digitized H&E-stained images of TCGA samples remain underutilized. To highlight this resource, we present mappings of tumor-infiltrating lymphocytes (TILs) based on H&E images from 13 TCGA tumor types. These TIL maps are deriv …

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