Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice
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Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice

Kitada, Yoshihiko;Kajita, Kazuo;Taguchi, Koichiro;Mori, Ichiro;Yamauchi, Masahiro;Ikeda, Takahide;Kawashima, Mikako;Asano, Motochika;Kajita, Toshiko;Ishizuka, Tatsuo;Banno, Yoshiko;Kojima, Itaru;Chun, Jerold;Kamata, Shotaro;Ishii, Isao;Morita, Hiroyuki;
endocrinology 2016 Vol. 157 pp. 1839-1851
196
yoshihiko2016endocrinologyblockade

Abstract

Abstract. Sphingosine 1-phosphate (S1P) is known to regulate insulin resistance in hepatocytes, skeletal muscle cells, and pancreatic β-cells. Among its 5 cogn

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