TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa
Abstract
Flagella and cilia are critical cellular organelles that provide a means for cells to sense and progress through their environment. The central component of flagella and cilia is the axoneme, which comprises the "9+2" microtubule arrangement, dynein arms, radial spokes, and the nexin-dynein regulato …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
Mice
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
male
N.I.H.
Extramural
mutation
Crosses
proteins / genetics*
cytoskeleton / metabolism
proteins / physiology
hek293 cells
pmid:28630322
pmc5502601
doi:10.1073/pnas.1621279114
julio m castaneda
rong hua
mingxi liu
adenosine triphosphate / metabolism
axoneme / metabolism
chlamydomonas / metabolism
cilia / metabolism
dyneins / metabolism*
flagella / metabolism
green fluorescent proteins / metabolism
homozygote
microtubules / metabolism
sperm motility*
spermatids / metabolism
spermatozoa / physiology*
testis / metabolism
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118870
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