HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis

HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis

Henter JI;Horne A;Aricó M;Egeler RM;Filipovich AH;Imashuku S;Ladisch S;McClain K;Webb D;Winiarski J;Janka G;;
pediatric blood & cancer 2007 Vol. 48 pp. -
355
ji2007pediatrichlh-2004:

Abstract

In HLH-94, the first prospective international treatment study for hemophagocytic lymphohistiocytosis (HLH), diagnosis was based on five criteria (fever, splenomegaly, bicytopenia, hypertriglyceridemia and/or hypofibrinogenemia, and hemophagocytosis). In HLH-2004 three additional criteria are introd …

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