Injury factors alter miRNAs profiles of exosomes derived from islets and circulation
Abstract
Islets damage is a major abnormality underling diabetes. Recent studies suggested the value of exosomes in diagnosis. This study aimed to investigate the impact of injury factors on the miRNA profiles of islet exosomes and determine whether circulating exosomal miRNAs is suitable as biomarkers of is …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
adult
male
middle aged
microscopy
micrornas / metabolism*
glucose / metabolism
inbred icr
electron
diabetes mellitus
pmid:30552311
pmc6326691
doi:10.18632/aging.101689
qi fu
hemin jiang
tao yang
type 1 / metabolism
type 2 / metabolism
exosomes / genetics
exosomes / metabolism*
glucose intolerance / metabolism
islets of langerhans / metabolism*
islets of langerhans / ultrastructure
transmission
nanoparticles
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118333
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