Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial

Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial

Emily L Webb, Patrice A Mawa, Juliet Ndibazza, Dennison Kizito, Alice Namatovu, Jacqueline Kyosiimire-Lugemwa, Bridget Nanteza, Margaret Nampijja, Lawrence Muhangi, Patrick W Woodburn, Hellen Akurut, Harriet Mpairwe, Miriam Akello, Nancy Lyadda, Joseph Bukusuba, Macklyn Kihembo, Moses Kizza, Robert Kizindo, Juliet Nabulime, Christine Ameke, Proscovia B Namujju, Robert Tweyongyere, Moses Muwanga, James AG Whitworth, Alison M Elliott;Emily L Webb;Patrice A Mawa;Juliet Ndibazza;Dennison Kizito;Alice Namatovu;Jacqueline Kyosiimire-Lugemwa;Bridget Nanteza;Margaret Nampijja;Lawrence Muhangi;Patrick W Woodburn;Hellen Akurut;Harriet Mpairwe;Miriam Akello;Nancy Lyadda;Joseph Bukusuba;Macklyn Kihembo;Moses Kizza;Robert Kizindo;Juliet Nabulime;Christine Ameke;Proscovia B Namujju;Robert Tweyongyere;Moses Muwanga;James AG Whitworth;Alison M Elliott;
Lancet (London, England) 2011 Vol. 377 pp. 52-
172
elliott2011lanceteffect

Abstract

Helminth infections affect the human immune response. We investigated whether prenatal exposure to and treatment of maternal helminth infections affects development of an infant's immune response to immunisations and unrelated infections.In this randomised, ...

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