The role of TH1 and TH2 cells in a rodent malaria infection
Abstract
CD4+ T cells play a major role in protective immunity against the blood stage of malaria, but the mechanism of protection is unclear. By adoptive transfer of cloned T cell lines, direct evidence is provided that both TH1 and TH2 subsets of CD4+ T cells can protect mice against Plasmodium chabaudi ch …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
Antibodies
cell line
malaria / immunology*
t-lymphocyte subsets / immunology*
lymphocyte depletion
inbred strains
pmid:8100366
doi:10.1126/science.8100366
a w taylor-robinson
r s phillips
f y liew
protozoan / biosynthesis
arginine / analogs & derivatives
arginine / pharmacology
cd4-positive t-lymphocytes / immunology*
immunoglobulin g / biosynthesis*
nitrates / blood
nitric oxide / metabolism*
plasmodium chabaudi / immunology*
omega-n-methylarginine
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118207
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