[Safety and immunogenicity analysis of recombinant （hansenula polymorpha) hepatitis B vaccine （CpG ODN adjuvant) among adults: the preliminary results of phase I clinical trial]
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[Safety and immunogenicity analysis of recombinant （hansenula polymorpha) hepatitis B vaccine （CpG ODN adjuvant) among adults: the preliminary results of phase I clinical trial]

Liang ZZ;Shao Y;Wang SY;Yan CF;Chen B;Zhang J;Chen YP;Hu XS;Lyu HK;;
zhonghua yu fang yi xue za zhi [chinese journal of preventive medicine] 2020 Vol. 54 pp. -
312
zz2020zhonghua[safety

Abstract

Objective: To evaluate the safety and immune effect of recombinant hepatitis B vaccine （CpG ODN adjuvant). Methods: On Oct. 26, 2016, we launched volunteer recruitment in Kaihua county, Quzhou city, Zhejiang Province. In the randomized, double-blind, controlled trial, a total of 48 sub …

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National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine English Abstract pmid:32842315 doi:10.3760/cma.j.cn112150-20200401-00490 z z liang y shao h k lyu

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