Effectiveness of 7-Valent Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease in HIV-Infected and -Uninfected Children in South Africa: A Matched Case-Control Study

Effectiveness of 7-Valent Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease in HIV-Infected and -Uninfected Children in South Africa: A Matched Case-Control Study

Cheryl Cohen, Claire von Mollendorf, Linda de Gouveia, Nireshni Naidoo, Susan Meiring, Vanessa Quan, Vusi Nokeri, Melony Fortuin-de Smit, Babatyi Malope-Kgokong, David Moore, Gary Reubenson, Mamokgethi Moshe, Shabir A. Madhi, Brian Eley, Ute Hallbauer, Ranmini Kularatne, Laura Conklin, Katherine L. O'Brien, Elizabeth R. Zell, Keith Klugman, Cynthia G. Whitney, Anne von Gottberg, David Moore, Charl Verwey, Sheeba Varughese, Moherndran Archary, Fathima Naby, Khathija Dawood, Ramola Naidoo, Gene Elliott, Ute Hallbauer, Brian Eley, James Nuttall, Louise Cooke, Heather Finlayson, Helena Rabie, Andrew Whitelaw, Dania Perez, Pieter Jooste, Dhamiran Naidoo, Ranmini Kularatne, Gary Reubenson, Cheryl Cohen, Linda de Gouveia, Mignon du Plessis, Nevashan Govender, Susan Meiring, Vanessa Quan, Claire von Mollendorf, Melony Fortuin-de Smidt, Nireshni Naidoo, Babatyi Malope-Kgokong, Vusi Nokeri, Relebohile Ncha, Sonwabo Lindani, Anne von Gottberg, Barry Spies, Lino Sono, Phasweni Maredi, Ken Hamese, Mamokgethi Moshe, Maphosane Nchabeleng, Ntombenhle Ngcobo, Johann van den Heever, Shabir Madhi, Laura Conklin, Jennifer Verani, Cynthia Whitney, Elizabeth Zell, Jennifer Loo, George Nelson, Keith Klugman, Katherine O'Brien;Cheryl Cohen;Claire von Mollendorf;Linda de Gouveia;Nireshni Naidoo;Susan Meiring;Vanessa Quan;Vusi Nokeri;Melony Fortuin-de Smit;Babatyi Malope-Kgokong;David Moore;Gary Reubenson;Mamokgethi Moshe;Shabir A. Madhi;Brian Eley;Ute Hallbauer;Ranmini Kularatne;Laura Conklin;Katherine L. O'Brien;Elizabeth R. Zell;Keith Klugman;Cynthia G. Whitney;Anne von Gottberg;David Moore;Charl Verwey;Sheeba Varughese;Moherndran Archary;Fathima Naby;Khathija Dawood;Ramola Naidoo;Gene Elliott;Ute Hallbauer;Brian Eley;James Nuttall;Louise Cooke;Heather Finlayson;Helena Rabie;Andrew Whitelaw;Dania Perez;Pieter Jooste;Dhamiran Naidoo;Ranmini Kularatne;Gary Reubenson;Cheryl Cohen;Linda de Gouveia;Mignon du Plessis;Nevashan Govender;Susan Meiring;Vanessa Quan;Claire von Mollendorf;Melony Fortuin-de Smidt;Nireshni Naidoo;Babatyi Malope-Kgokong;Vusi Nokeri;Relebohile Ncha;Sonwabo Lindani;Anne von Gottberg;Barry Spies;Lino Sono;Phasweni Maredi;Ken Hamese;Mamokgethi Moshe;Maphosane Nchabeleng;Ntombenhle Ngcobo;Johann van den Heever;Shabir Madhi;Laura Conklin;Jennifer Verani;Cynthia Whitney;Elizabeth Zell;Jennifer Loo;George Nelson;Keith Klugman;Katherine O'Brien;
clinical infectious diseases: an official publication of the infectious diseases society of america 2014 Vol. 59 pp. 808-
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o'brien2014clinicaleffectiveness

Abstract

Background. South Africa introduced 7-valent pneumococcal conjugate vaccine (PCV7) in April 2009 using a 2 + 1 schedule (6 and 14 weeks and 9 months). We estimated the effectiveness of ≥2 PCV7 doses against invasive pneumococcal disease ...

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