Impaired developmental competence of oocytes in adult prenatally androgenized female rhesus monkeys undergoing gonadotropin stimulation for in vitro fertilization
Abstract
To determine whether prenatal T propionate exposure beginning gestational d 40-44 (early-treated) or 100-115 (late-treated) affects oocyte competence, five early-treated and five late-treated prenatally androgenized and five normal monkeys underwent recombinant human FSH injections with oocyte-retri …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
pregnancy
research support
u.s. gov't
female
david h abbott
daniel a dumesic
P.H.S.
testosterone / pharmacology*
hormones / blood
prenatal exposure delayed effects*
embryo
embryonic and fetal development
recombinant proteins / pharmacology
pmid:11889174
doi:10.1210/jcem.87.3.8287
r dee schramm
cellular senescence / physiology
mammalian / physiology
fertilization
fertilization in vitro*
follicle stimulating hormone / pharmacology*
follicular fluid / metabolism
gonadal steroid hormones / pharmacology*
hormones / metabolism
macaca mulatta / embryology
oocytes / physiology*
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115726
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