Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With Recurrent Clostridium difficile Infection: A Randomized Clinical Trial

Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With Recurrent Clostridium difficile Infection: A Randomized Clinical Trial

Christine H. Lee;Theodore Steiner;Elaine O. Petrof;Marek Smieja;Diane Roscoe;Anouf Nematallah;J. Scott Weese;Stephen Collins;Paul Moayyedi;Mark Crowther;Mark J. Ropeleski;Padman Jayaratne;David Higgins;Yingfu Li;Neil V. Rau;Peter T. Kim;
JAMA 2016 Vol. 315 pp. 142-149
231
lee2016jamafrozen

Abstract

This randomized noninferiority trial assessed whether FMT using frozen stool is noninferior to transplantation using fresh stool in resolving diarrhea among adult patients with recurrent or refractory Clostridium difficile infection.

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