Effect of Arg399Gln single-nucleotide polymorphism in XRCC1 gene on survival rate of Indian squamous cell head-and-neck cancer patients
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Effect of Arg399Gln single-nucleotide polymorphism in XRCC1 gene on survival rate of Indian squamous cell head-and-neck cancer patients

Dutta D;Abarna R;Shubham M;Subbiah K;Duraisamy S;Chinnusamy R;Anbalagan M;;
journal of cancer research and therapeutics 1970 Vol. 16 pp. -
236
d1970journaleffect

Abstract

This study suggests that HNSCC patients with Gln substitution in place of Arg at position 399 (both homozygous and heterozygous) in XRCC1 protein have significantly inferior survival functions, higher recurrence rate, and events after radical treatment.

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National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine pmid:32719266 doi:10.4103/jcrt.jcrt_476_18 debnarayan dutta rajadurai abarna moorthy anbalagan

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