Application of fluoroquinolone pharmacodynamics
Abstract
Pharmacodynamics provides a rational basis for optimizing dosing regimens by describing the relationship between drug, host and antimicrobial effect. The successful identification of meaningful pharmacodynamic outcome parameters can, therefore, greatly assist clinicians in making objective prescribi …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
bacteria
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
microbial sensitivity tests
fluoroquinolones
species specificity
j c rotschafer
pmid:11062185
doi:10.1093/jac/46.5.669
d h wright
g h brown
anti-infective agents / pharmacokinetics*
area under curve*
anaerobic / metabolism
clinical trials as topic / methods
gram-negative bacterial infections / metabolism
gram-positive bacterial infections / metabolism*
pneumococcal infections / metabolism
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115153
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