Recombinant human eosinophil-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus
Domachowske JB;Dyer KD;Bonville CA;Rosenberg HF;;
The Journal of infectious diseases1998Vol. 177pp. -
373
jb1998therecombinant
Abstract
A dose-dependent decrease in infectivity was observed on introduction of eosinophils into suspensions of respiratory syncytial virus group B (RSV-B). This antiviral effect was reversed by ribonuclease inhibitor, suggesting a role for the eosinophil secretory ribonucleases. Recombinant eosinophil-der …