Natural transmission of bat-like SARS-CoV-2ΔPRRA variants in COVID-19 patients

Natural transmission of bat-like SARS-CoV-2ΔPRRA variants in COVID-19 patients

Wong, Yik Chun;Lau, Siu Ying;To, Kelvin Kai Wang;Mok, Bobo Wing Yee;Li, Xin;Wang, Pui;Deng, Shaofeng;Woo, Kin Fai;Du, Zhenglong;Li, Cun;Zhou, Jie;Chan, Jasper Fuk Woo;Yuen, Kwok Yung;Chen, Honglin;Chen, Zhiwei;
clinical infectious diseases pp. -
121
chunclinicalnatural

Abstract

AbstractBackground. SARS-CoV-2 contains the furin cleavage PRRA motif in the S1/S2 region, which enhances viral pathogenicity but is absent in closely related

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