A Double-blind, Randomized Phase 2 Controlled Trial of Intradermal Hepatitis B Vaccination With a Topical Toll-like Receptor 7 Agonist Imiquimod, in Patients on Dialysis
Hung, Ivan Fan-Ngai;Yap, Desmond Yat-Hin;Yip, Terence Pok-Siu;Zhang, Ricky Ruiqi;To, Kelvin Kai-Wang;Chan, Kwok-Hung;Tang, Sydney Chi-Wai;Lui, Sing-Leung;Levin, Yotam;Kochba, Efrat;Lau, Johnson Yiu-Nam;Yuen, Man-Fung;Chan, Tak-Mao;Yuen, Kwok-Yung;
clinical infectious diseasespp. -
162
fan-ngaiclinicala
Abstract
This study demonstrated that topical imiquimod (TLR7 agonist) before intradermal hepatitis B vaccination was safe, with significantly better seroprotection than