Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience

Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience

Ryuichi Hirano;Yuichi Sakamoto;Kumiko Kudo;Motoki Ohnishi;
Infection and drug resistance 2015 Vol. 8 pp. 199--205
179
hirano2015retrospectiveinfection

Abstract

Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience Ryuichi Hirano,1 Yuichi Sakamoto,2 Kumiko Kudo,1 Motoki Ohnishi31Department of Pharmacy, Aomori Prefectural Central Hospital, Aomori, Japan; 2Laboratory Medicine and Blood transfusion, Aomori Prefectural Central Hospital, Aomori, Japan; 3General Medicine, Aomori Prefectural Central Hospital, Aomori, JapanAbstract: The mortality rate for candidemia is approximately 30%–60%. However, prognostic factors in patients with candidemia have not yet been elucidated in detail. The aim of the present study was to analyze prognostic factors for candidemia using the mortality rate and Candida isolates of patients with candidemia. Seventy-five patients with candidemia were analyzed between January 2007 and December 2013. The main outcome of this study was the 30-day mortality rate after the diagnosis of candidemia. The acute physiology and chronic health evaluation II score (APACHE II score) was measured in 34 patients (45.3%). Odds ratios (ORs) for death due to candidemia were analyzed using a multivariate stepwise logistic regression analysis. Twenty (26.6%) patients died within 30 days of being diagnosed with candidemia. Non-survivors had a significantly higher APACHE II score

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